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type="text/css"></style> <div id="ct" class="ct2 wp cl"> <div class="mn"> <div class="bm_haa cl"> <div class="bm_h cl"> <a href="http://www.oecr.com/portal.php?mod=rss&catid=57" class="y xi2 rss" target="_blank" title="RSS">订阅</a><h1 class="xs2">文章</h1> </div></div> <div class="kjkjb"> <div class="bm vw" style="margin-bottom:0;"> <div class="h hm"> <div class="zxtoux"><img src="http://www.oecr.com/uc_server/avatar.php?uid=115533&size=small" /></div> <h1 class="ph">KAIST开发高感度纳米光学测定技术 </h1> <p class="xg1"> 时间：2011-2-13 14:13<a class="zz" href="home.php?mod=space&uid=115533">作者：娆娆</a> 阅读<em id="_viewnum">(1129)</em> 评论: <a href="http://www.oecr.com/portal.php?mod=comment&id=1594&idtype=aid" title="查看全部评论"><em id="_commentnum">1</em></a></p> <div class="zxfb" ><a href="http://www.oecr.com/portal.php?mod=rss&catid=57" class="y xi2 rss" target="_blank" title="RSS">订阅</a></div> </div> <!--[diy=diysummarytop]--><div id="diysummarytop" class="area"></div><!--[/diy]--> <div class="s"> <div class="ss"><div><span>导读： </span>KAIST(韩国科学技术院•总长：徐楠杓)26日发表了生物及脑工学系的郑基勋教授研究组为检出小分子生化合物(small molecules)，开发了划时代的高感度纳米光学测定技术。</div> </div> <!--[diy=diysummarybottom]--><div id="diysummarybottom" class="area"></div><!--[/diy]--> <div class="d"> <!--[diy=diycontenttop]--><div id="diycontenttop" class="area"></div><!--[/diy]--> <table cellpadding="0" cellspacing="0" class="vwtb"><tr><td id="article_content">将现存的世界最高水准的检出局限可以提高数百倍以上的技术被国内研究组开发。 KAIST(韩国科学技术院•总长：徐楠杓)26日发表了生物及脑工学系的郑基勋教授研究组为检出小分子生化合物(small molecules)，开发了划时代的高感度<a href="http://material.oecr.com" target="_blank" class="relatedlink">纳米</a>光学测定技术。 <BR><BR>小分子生化合物是指分子量在小生体内的分子群，主要负责多种细胞的细胞膜在进出时转达细胞间的信号等重要作用，最近在制药业界也利用小分子生化合物进行新药开发的相关研究，得到关心。<BR><BR>郑教授研究组利用比人体发丝断面小70万倍的纳米流体管内的流动特性，将保有纳米(nM)中心水准浓度的极微量的小分子生化合物的浓度局部的增加，今后，与纳米Plasmonic光学技术接木，将测定的光度提高1万倍以上，无需使用另外的生化学处理，在1秒内可以成功地区别类似多巴胺(Dopamine)与GABA的神经转达物质。 <BR><BR>此次研究结果，今后不仅利用在小分子生化合物的多种国际新药开发上，而且寄予利用在类似阿尔茨海默病的退行性神经疾患的早期诊断或脑机能诊断技术上。<BR><BR>研究主要是在吴永宰博士生主导下进行，并且在德国发刊的纳米领域国际著名<a 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